Radiesse® combines two approaches in a single treatment: This biostimulator can subtly restore lost volume while simultaneously stimulating the body’s own production of important skin structures, such as collagen. The result is a refreshed, firmer appearance that preserves facial features without a pronounced “filler look.”
15–30 minutes
0–4 months
9–18 months
1-2
Radiesse® is an injectable biostimulator based on calcium hydroxylapatite (CaHA) that smooths wrinkles while stimulating the body’s own collagen production. The product, manufactured by Merz, consists of tiny CaHA microspheres (tiny spheres) embedded in a gel-like carrier material. The active ingredient is particularly well-tolerated because its chemical composition is similar to that of natural hydroxyapatite, which is also found in our bones and teeth. Unlike a traditional volume filler, Radiesse® does not simply fill in wrinkles but stimulates the skin to regenerate from within.
After the injection, two things happen: First, the gel provides an immediate, moderate volumizing effect. Then, the CaHA microspheres set a longer-term process in motion. They serve, in a sense, as a contact and scaffolding structure for the cells in the tissue and exert mechanical stimuli on fibroblasts. These skin cells then begin to produce increased amounts of new components of the body’s own connective tissue —particularly collagen, but also elastin and tiny blood vessels.
The initial volumizing effect thus gradually transitions into a biostimulative effect: Rather than simply adding volume, Radiesse® supports the remodeling of the body’s own tissue structure.
Radiesse® can serve various purposes: When used undiluted, the filler provides targeted support and contouring; when diluted, it improves skin quality over a larger area.
Typical treatment areas for undiluted Radiesse® include:
If Radiesse® is diluted further, the product spreads more evenly throughout the tissue. The filler effect becomes less pronounced, while the biostimulative effect takes center stage. This makes this form of treatment suitable, for example, for firming the skin and improving its quality on the face, neck, and décolleté.
Important: Treatments with diluted Radiesse® are considered off-label, meaning they fall outside the product’s originally approved indications. However, they are well-established in aesthetic medicine and have been thoroughly studied scientifically.
For us, the eye area is a definite no-go. Other products are also recommended for the lips and superficial fine lines.
With Radiesse®, you can usually expect only a very subtle immediate effect—rather, a gentle lifting and rejuvenating effect that develops over the course of several months —while preserving facial expressions and without excessive volume buildup.
When used in diluted form, the immediate effect is much less prominent. The focus here is primarily on the gradual improvement of skin quality.
Radiesse® is considered one of the most thoroughly studied fillers, but like any injectable treatment, it is not entirely risk-free. Mild, temporary reactions such as swelling, redness, bruising, or a feeling of pressure are common; they usually subside within a few days.
True complications, on the other hand, are rare. One of the most comprehensive safety analyses of Radiesse® (21 studies, over 5,000 treatments) found an overall complication rate of about 3 percent. These complications consisted almost exclusively of nodules, which were easily treatable in most cases. Persistent, delayed inflammation remained an isolated occurrence. Incidentally, when used in a diluted form, the product spreads more evenly throughout the tissue, which can further reduce the risk.
Important to know: Like all hyaluronic acid fillers, biostimulators must not be injected into blood vessels, as this can lead to vascular occlusion with serious consequences. Unlike hyaluronic acid, Radiesse® cannot be dissolved with an enzyme. This is precisely why the treatment must be performed by an experienced physician: a precise injection technique, targeting the correct tissue layer, and a thorough understanding of vascular anatomy are crucial for safety. By the way: When used in a diluted form, Radiesse® spreads more evenly, which can further reduce certain risks, such as the formation of nodules.
The cost of a Radiesse® treatment starts at €590 and depends on the desired treatment and the area to be treated.
Overview of Radiesse® treatment prices:
Not every age-related change occurs in the same layer of the skin. For this reason, depending on the individual case, Radiesse® can be effectively combined with other procedures:
One thing is clear: For optimal results, a personalized approach is always necessary. At GoAesthetic, we’d be happy to consult with you in person to determine what best suits your treatment goals.
At GoAesthetic, a Radiesse® treatment costs €590 (1.5 ml). The total cost depends on which areas are being treated and how many vials are needed. During your consultation, you’ll receive a clear treatment plan with a fixed price upfront—no surprises.
As a general guideline, you can expect the effects to last an average of about 9 to 18 months. However, how long the results remain visible varies from person to person and depends, among other things, on the treatment area, the amount of product used or its dilution, and individual tissue characteristics.
There’s no one-size-fits-all answer to that. Radiesse® is supplied in 1.5-ml vials. How much you’ll need depends on the treatment area and the extent of volume loss: For a single area, one injection is often sufficient; for multiple areas or contouring along the jawline, two to three injections are usually required. We deliberately follow the principle of “building up gradually rather than overcorrecting,” because a natural-looking result can always be enhanced later. We’ll determine the exact amount together during your consultation.
There is no one-size-fits-all answer—both procedures have different strengths. Hyaluronic acid is particularly well-suited for immediately visible, precisely sculptable volume and can be dissolved with hyaluronidase if necessary. Radiesse® combines a moderate immediate effect with biostimulation and focuses more on the gradual buildup of collagen and tissue structure.
Which treatment is more suitable therefore depends primarily on whether the focus is on volume and contour or rather on tightening and skin quality.
Yes, Radiesse® is completely broken down by the body. The gel-like carrier material is eliminated from the body relatively quickly, while the CaHA microspheres remain in the tissue for a significantly longer period of time and are broken down gradually. According to studies, they are no longer detectable after 2.5 years at the latest.
No, the eye area is a definite no-go for us when it comes to Radiesse®. There are better options for the sensitive eye area, such as polynucleotides for gentle skin regeneration or, depending on your specific situation, a careful injection of hyaluronic acid. The best way to determine what’s right for you is to discuss it in person.
The most important rules: Avoid intense exercise for at least 2 days, avoid strong sunlight or tanning beds for a few days, and avoid saunas or steam rooms for 1 week. You should also gently massage the treated area a few times a day for 3 days.
Last updated: September 4, 2026
GoAesthetic
Center for aesthetic treatments
Address:
Magdalenenstraße 22/1
1060 Vienna
E-mail: kontakt@goaesthetic.at
Phone: 01/ 417 12 21
“Very nice doctors office, the staff is very friendly and you feel comfortable right away! After the first treatment I already saw a great result! Can definitely recommend.”
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